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Valeant Pharmaceuticals International Inc. is eyeing another takeover target in ISTA Pharmaceuticals Inc., but it may have to go the hostile route to win the rights to the ophthalmic drugmaker.

Ken deRegt will retire as head of fixed income at Morgan Stanley and be replaced by Michael Heaney and Robert Rooney. For other updates launch today's Movers & shakers slideshow.
Apax Partners offers $1.1 billion for Rue21, the same teenage fashion chain it took public in 2009. More video