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Medical devices Carbylan Palo Alto, Calif.-based medical device company Carbylan BioSurgery Inc. has raised a $20 million Series B led by Vivo Ventures of Palo Alto, Calif. Also participating were existing investors Alta Partners of San Francisco and InterWest Partners LLC of Menlo Park, Calif. Albert Cha, Managing Partner at Vivo Ventures, will join Carbylan's board of directors. The company is developing bioresponsive medical products for osteoarthritis and chronic rhinosinusitis. The proceeds will be used to advance Carbylan's lead product candidates that allows delivery of biomaterial-based medical devices as injectable liquids. --G.W. Pharmaceuticals Yaupon Yaupon Therapeutics Inc. has received a $14.5 million third round of financing that will allow the Radnor, Pa.-based drug maker to advance its lead candidate through the final stages of clinical trials. The funding was led by Vivo Ventures of Palo Alto, Calif., joined by Palo Alto Investors LLC and unnamed private investors. The round gives Yaupon a total of $21 million in venture capital since it was founded in 2002. Prior to the Series C, Yaupon raised only $7 million in outside money. A November 2006 Series B for $4 million was led by Osage Ventures of Bala Cynwyd, Pa., with a follow-on investment by BioAdvance Greenhouse Fund of Philadelphia, and with participation by Ben Franklin Technology Partners of Philadelphia, and TDH Capital of Radnor. The three participating investors have all made sub-$1 million investments to Yaupon in the preceding four years. The company's lead candidate, Clearazide, is a topical cytotoxic agent for the treatment of cutaneous T-cell lymphoma. Clearazide is currently in pivotal phase 2 clinical trials and may be on the market in 2009. --G.W. Semiconductors Quantenna Sunnyvale, Calif.-based wireless chip developer Quantenna Communications Inc. raised $12.7 million in a Series B round led by Sigma Partners of Menlo Park, Calif., to complete development and begin marketing multiple antenna semiconductors late next year. The company also brought in Germany's Grazia Equity GmbH as a new investor, joining returning backers Sequoia Capital and Venrock Associates, both of Menlo Park, to bring total investment to about $25 million. The deal is expected to allow the company to launch its first products for a broad spectrum of wireless markets, and begin volume production with Taiwan Semiconductor Manufacturing Co. Ltd. as its primary fabrication partner. --Clifford Carlsen Internet Youku.com Beijing-based Youku.com, an online video-sharing Web site in China, has completed a $25 million Series C funding. The capital came from Sutter Hill Ventures of Palo Alto, Calif., Farallon Capital Management LLC of San Francisco and Chengwei Ventures LLC of Shanghai, who had previously invested $15 million in Youku. The proceeds will be used to expand sales and marketing, as well as for R&D of the company's video service. Launched in November 2005, Youku claims to deliver more than 80 million video views on a daily basis. Youku has video strategic cooperation agreements with Sohu.com Inc., Baidu.com Inc. and Shanda Interactive Entertainment Ltd. --G.W. Yodle Local Internet advertising startup Yodle Inc. has raised a $12 million second round led by Draper Fisher Jurvetson with participation from existing investor Bessemer Venture Partners. Both investors are of Menlo Park, Calif. The New York-based startup's technology is targeted at making buying online ads simple and easy for small businesses. --G.W.  Deal Video
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